| Abstract | The clinical efficacy of sodium nucleinate (SN) combined with splenin and quercetin given for lingering Flexner's dysentery in a group of 43 patients was compared with that of routine therapy used in a group of the same number of patients. It has been established that the above drug combination favours the elimination of the pathological symptoms of dyspepsia, the arrest of bacterial isolation and normalization of the immune status. Provided the effect of the combined drug treatment is insufficient, the method of choice is the administration of gene engineering alpha 2-interferon (reaferon) in combination with tocopherol acetate and rectal suppositories containing methyluracil. |
| Authors | N D Iushchuk, V M Frolov, N A Peresadin |
| Journal | Terapevticheskiĭ arkhiv
(Ter Arkh)
Vol. 63
Issue 11
Pg. 19-22
( 1991)
ISSN: 0040-3660 USSR |
| Vernacular Title | Lechenie zatiazhnykh form dizenterii Fleksnera. |
| PMID | 1810053
(Publication Type: Comparative Study, English Abstract, Journal Article)
|
| Chemical References |
- Adjuvants, Immunologic
- Nucleic Acids
- RNA, Fungal
- Thymopoietins
- Quercetin
- thymopoietin III
- sodium nucleinate
|
| Topics |
- Adjuvants, Immunologic
(therapeutic use)
- Adult
- Chronic Disease
- Drug Evaluation
- Drug Therapy, Combination
- Dysentery, Bacillary
(drug therapy, immunology)
- Humans
- Immunity, Cellular
(drug effects)
- Middle Aged
- Nucleic Acids
(therapeutic use)
- Quercetin
(therapeutic use)
- RNA, Fungal
(therapeutic use)
- Shigella flexneri
- Thymopoietins
(therapeutic use)
- Time Factors
|
