Increased activity on In-111 octreotide imaging due to radiation fibrosis.

Abstract

Indium-111 octreotide scintigraphy is a useful investigation in the diagnosis and staging neuroendocrine or nonendocrine malignancies such as carcinoid, granulomas, small cell lung cancer, medullary thyroid carcinoma, and others. Tumors with large numbers of somatostatin receptors can be accurately imaged and this can be useful in guiding treatment. Although uncommon, false-positives studies have been reported and often the cause is unexplained but assumed to be a high number of somatostatin receptors in other pathology. We present a case with increased uptake resulting in a scan due to pulmonary fibrosis.

• Authors: Leo Ha, Robert Mansberg, Diep Nguyen, Chuong Bui
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 33 Issue 1 Pg. 46-8 (Jan 2008) ISSN: 0363-9762 [Print] United States
• PMID: 18097260 (Publication Type: Case Reports, Journal Article)

Chemical References

• Radiopharmaceuticals
• indium-111-octreotide
• Octreotide

Topics

• Breast Neoplasms (radiotherapy)
• Diagnosis, Differential
• False Positive Reactions
• Female
• Humans
• Middle Aged
• Octreotide (analogs & derivatives)
• Radiation Pneumonitis (diagnostic imaging)
• Radiopharmaceuticals
• Tomography, Emission-Computed