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[A case of therapy-related acute myeloid leukemia associated with inv(16)]

AbstractThe inv(16)(p13q22) is found in de novo AML and is closely associated with the FAB subtype M4eo. The inv(16) is rarely reported in therapy-related AML (t-AML) patients. Herein, we report a case of t-AML with inv(16) after combination chemotherapy using antimitotic agent and alkylating agent (cis-platin-paclitaxel) for ovarian serous cystadenocarcinoma.
AuthorsSo-Young Lee, Myungshin Kim, Jihyang Lim, Yonggoo Kim, Kyungja Han, Sung Yong Kim, Hee Je Kim, In-Yang Park (Affiliation: Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.)
JournalThe Korean journal of laboratory medicine (Korean J Lab Med) Vol. 27 Issue 1 Pg. 19-21 (Feb 2007) ISSN: 1598-6535 Korea (South)
PMID18094545 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Antimitotic Agents
  • TP protocol
  • Taxoids
  • Cisplatin
Topics
  • Antimitotic Agents (adverse effects, therapeutic use)
  • Antineoplastic Combined Chemotherapy Protocols (adverse effects, therapeutic use)
  • Chromosomes, Human, Pair 16 (genetics)
  • Cisplatin (adverse effects, therapeutic use)
  • Female
  • Humans
  • Inversion, Chromosome
  • Leukemia, Myeloid, Acute (chemically induced, pathology)
  • Middle Aged
  • Taxoids (adverse effects, therapeutic use)