[A case of therapy-related acute myeloid leukemia associated with inv(16)].

Abstract

The inv(16)(p13q22) is found in de novo AML and is closely associated with the FAB subtype M4eo. The inv(16) is rarely reported in therapy-related AML (t-AML) patients. Herein, we report a case of t-AML with inv(16) after combination chemotherapy using antimitotic agent and alkylating agent (cis-platin-paclitaxel) for ovarian serous cystadenocarcinoma.

• Authors: So-Young Lee, Myungshin Kim, Jihyang Lim, Yonggoo Kim, Kyungja Han, Sung Yong Kim, Hee Je Kim, In-Yang Park
• Journal: The Korean journal of laboratory medicine (Korean J Lab Med) Vol. 27 Issue 1 Pg. 19-21 (Feb 2007) ISSN: 1598-6535 [Print] Korea (South)
• PMID: 18094545 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antimitotic Agents
• Taxoids
• Paclitaxel
• Cisplatin

Topics

• Antimitotic Agents (adverse effects, therapeutic use)
• Antineoplastic Combined Chemotherapy Protocols (adverse effects, therapeutic use)
• Chromosome Inversion
• Chromosomes, Human, Pair 16 (genetics)
• Cisplatin (adverse effects, therapeutic use)
• Female
• Humans
• Leukemia, Myeloid, Acute (chemically induced, pathology)
• Middle Aged
• Paclitaxel
• Taxoids (adverse effects, therapeutic use)