High prevalence of sleep disorders at the time of CKD diagnosis.

Sleep disorders are very common in adult and children on maintenance hemodialysis and are not cured by renal transplantation.
Studies in our laboratory of patients with a mean plasma creatinine concentration of 2 mg/dL, studied within 2 months of chronic kidney disease (CKD) diagnosis, have detected a high prevalence of sleep disorders that could not be explained by using the factors prevalent in hemodialysis patients.
To understand if the intrusiveness of the disease is a cause for the high prevalence of sleep disorders in early CKD, we have assessed, by means of a questionnaire, sleep disorders within 1 month from the diagnosis of renal dysfunction.
A total of 100 CKD patients with a mean estimated creatinine clearance of 59.1 +/- 26.7 mL/min were studied. The prevalence of sleep disorders was 89%.
We believe this high prevalence might represent the effects of disease's intrusiveness and difficulty in coping with the disease.
AuthorsRosa Maria De Santo, Concetta Maria Cesare, Marilù Bartiromo, Massimo Cirillo
JournalJournal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation (J Ren Nutr) Vol. 18 Issue 1 Pg. 104-6 (Jan 2008) ISSN: 1532-8503 [Electronic] United States
PMID18089454 (Publication Type: Journal Article)
Chemical References
  • Hypnotics and Sedatives
  • Parathyroid Hormone
  • Urea
  • Adult
  • Chronic Disease
  • Female
  • Humans
  • Hypnotics and Sedatives (therapeutic use)
  • Kidney Diseases (blood, complications)
  • Kidney Failure, Chronic (blood, complications)
  • Male
  • Middle Aged
  • Parathyroid Hormone (blood)
  • Prevalence
  • Sleep Wake Disorders (blood, epidemiology, psychology)
  • Surveys and Questionnaires
  • Urea (blood)

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