The important and diverse roles of antibodies in the host response to Borrelia infections.

Abstract

Antibodies are of critical importance in the host response to tick-borne Borrelia species that cause relapsing fever and Lyme disease. Recent studies on the role of various B cell subsets in the host response to Borrelia, complement-independent, bactericidal antibodies, and diagnostics led to this review that focuses on the array of functions that antibodies to Borrelia can perform.

• Authors: T J LaRocca, J L Benach
• Journal: Current topics in microbiology and immunology (Curr Top Microbiol Immunol) Vol. 319 Pg. 63-103 ( 2008) ISSN: 0070-217X [Print] Germany
• PMID: 18080415 (Publication Type: Journal Article, Review)

Chemical References

• Antibodies, Bacterial
• Antigens, Bacterial
• Complement System Proteins

Topics

• Animals
• Antibodies, Bacterial (biosynthesis, blood, immunology)
• Antigens, Bacterial (immunology, metabolism)
• Autoimmunity
• B-Lymphocyte Subsets (immunology, metabolism)
• Borrelia (immunology, pathogenicity)
• Complement System Proteins (immunology, metabolism)
• Humans
• Insect Vectors (immunology, microbiology)
• Lyme Disease (diagnosis, immunology, microbiology)
• Relapsing Fever (diagnosis, immunology, microbiology)
• T-Lymphocytes (immunology)
• Ticks (immunology, microbiology)