| Abstract | We describe an obese child with severe obstructive sleep apnea syndrome in whom nocturnal frontal lobe seizures developed within a week after therapy was started with continuous positive airway pressure. The video polysomnographic study after the onset of nocturnal episodes showed 3 seizures: 2 starting from slow-wave sleep when he was sleeping with continuous positive airway pressure, and 1 from stage 2 non-rapid eye movement sleep when he was sleeping without continuous positive airway pressure. Cyclic alternating pattern analysis during the video polysomnography recorded after the onset of nocturnal seizures disclosed a high cyclic alternating pattern rate during slow-wave sleep, and the recording obtained after antiepileptic therapy began showed a low cyclic pattern analysis rate. In this child, we describe the non-rapid eye movement sleep instability induced by continuous positive airway pressure therapy might have had a role in triggering the nocturnal seizures. |
| Authors | Silvia Miano, Andrea Pelliccia, Melania Evangelisti, Jacopo Pagani, Maria Pia Villa
(Affiliation: Department of Pediatrics, Sleep Centre, University of Rome La Sapienza, S. Andrea Hospital, Rome, Italy.)
|
| Journal | Journal of child neurology
(J Child Neurol)
Vol. 23
Issue 1
Pg. 124-8
(Jan 2008)
ISSN: 0883-0738 Canada |
| PMID | 18079319
(Publication Type: Case Reports, Journal Article)
|
| Topics |
- Child, Preschool
- Continuous Positive Airway Pressure
(adverse effects)
- Electroencephalography
- Epilepsy
(etiology, physiopathology)
- Frontal Lobe
(physiopathology)
- Humans
- Male
- Obesity
(complications)
- Periodicity
- Polysomnography
- Sleep
(physiology)
- Sleep Apnea, Obstructive
(therapy)
- Sleep Disorders
(complications, physiopathology)
- Sleep, REM
(physiology)
|
