[Case of multi-drug resistant pulmonary tuberculosis with bilateral cavitary lesions successfully treated by surgical treatment].

Abstract

A case was 38 years old male. He was pointed out abnormal shadow on chest X-ray and complained respiratory infection symptoms. He had not past history of tuberculosis. He was diagnosed as multi-drug resistant tuberculosis (MDR-TB) in a certain hospital and was referred to our hospital to undergo treatment. His drug sensitivity test by Ogawa medium was resistant to all anti-tuberculosis drugs except for kanamycin (KM) and enviomycin (EVM). His chest X-ray revealed large cavities in the right upper field and infiltrations in the right lower field and small cavitary lesions in the left lower field. The right pneumonectomy was done because he took anti-tuberculosis drugs but his sputum examinations continued to be smear and culture positive without improvement of the lesions. After the surgical treatment (right pneumonectomy), he continued anti-tuberculosis drugs therapy and the chest X-ray improved including the collapse of left lower cavitary lesions. This case was a difficult case to treat because of bilateral cavitary lesions. However he was successfully treated by the surgical treatment.

• Authors: Masao Okumura, Hideo Ogata, Takashi Yoshiyama, Hiroyuki Kokutoh, Eiji Tadokoro, Motoko Kubota, Masako Ueyama, Masako Wada, Yutsuki Nakajima
• Journal: Kekkaku : [Tuberculosis] (Kekkaku) Vol. 82 Issue 11 Pg. 831-5 (Nov 2007) ISSN: 0022-9776 [Print] Japan
• PMID: 18078108 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antibiotics, Antitubercular

Topics

• Adult
• Antibiotics, Antitubercular (pharmacology, therapeutic use)
• Drug Resistance, Multiple
• Humans
• Male
• Mycobacterium tuberculosis (drug effects, isolation & purification)
• Pneumonectomy
• Sputum (microbiology)
• Treatment Outcome
• Tuberculosis, Pulmonary (diagnosis, microbiology, surgery)