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Imaging findings of central nervous system vasculitis associated with Goodpasture's Syndrome: a case report.

AbstractGlomerulonephritis and pulmonary hemorrhage are features of Goodpasture's syndrome. Goodpasture's syndrome accompanied with central nervous system (CNS) vasculitis is extremely rare. Herein, we report a rare case of CNS vasculitis associated with Goodpasture's syndrome in a 34-year-old man, who presented with a seizure and sudden onset of right sided weakness. He also had recurrent hemoptysis of one month's duration. Goodpasture's syndrome is histologically diagnosed by intense linear deposits of IgG along the glomerular basement membrane in both renal and lung tissues.
AuthorsJee Young Kim, Kook Jin Ahn, Jung Im Jung, So Lyung Jung, Bum Soo Kim, Seong Tae Hahn (Affiliation: Department of Radiology, St. Maryos Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.)
JournalKorean journal of radiology : official journal of the Korean Radiological Society (Korean J Radiol) 2007 Nov-Dec Vol. 8 Issue 6 Pg. 545-7 ISSN: 1229-6929 Korea (South)
PMID18071286 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Inflammatory Agents
  • Contrast Media
  • Immunoglobulin G
  • Methylprednisolone
Topics
  • Adult
  • Anti-Glomerular Basement Membrane Disease (complications, diagnosis, therapy)
  • Anti-Inflammatory Agents (administration & dosage)
  • Brain (pathology)
  • Contrast Media (administration & dosage)
  • Diagnosis, Differential
  • Fluorescent Antibody Technique
  • Hemoptysis (etiology)
  • Humans
  • Image Enhancement (methods)
  • Immunoglobulin G (immunology)
  • Kidney (ultrasonography)
  • Lung (pathology, radiography)
  • Magnetic Resonance Imaging
  • Male
  • Methylprednisolone (administration & dosage)
  • Muscle Weakness (etiology)
  • Plasmapheresis
  • Rare Diseases
  • Seizures (etiology)
  • Tomography, X-Ray Computed
  • Vasculitis, Central Nervous System (diagnosis, etiology, therapy)