[Treatment of central diabetes insipidus using oral DDAVP. Comparison with intranasal treatment].

Abstract

The Authors have done a clinical study on the efficacy of desmopressin (DDAVP) tablets in the treatment of central diabetes insipidus in 13 patients who were previously treated with intranasal DDAVP. A comparison has been made between peroral and intranasal forms of DDAVP measuring the urinary volume and osmolarity daily. The right dosage of DDAVP tablets was between 150 and 600 micrograms/die. The patients showed very good compliance during the 4 weeks of treatment with DDAVP.

• Authors: A Carraro, M Fano, E Porcella, V Bernareggi, M Giusti
• Journal: Minerva endocrinologica (Minerva Endocrinol) 1991 Jul-Sep Vol. 16 Issue 3 Pg. 141-5 ISSN: 0391-1977 [Print] Italy
• Vernacular Title: Trattamento del diabete insipido centrale con DDAVP per via orale. Confronto con il trattamento per via endonasale.
• PMID: 1806811 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Deamino Arginine Vasopressin

Topics

• Administration, Intranasal
• Administration, Oral
• Adolescent
• Adult
• Deamino Arginine Vasopressin (administration & dosage, pharmacology, therapeutic use)
• Diabetes Insipidus (drug therapy, urine)
• Diuresis (drug effects)
• Drug Evaluation
• Female
• Humans
• Male
• Middle Aged
• Osmolar Concentration
• Patient Acceptance of Health Care