Abstract |
The follicle ruptures at the time of ovulation and fills with blood, forming a corpus hemorrhagicum. Minor bleeding from the follicle into the abdominal cavity may cause peritoneal irritation and, when it occurs in a patient with a defect of primary hemostasis, hemoperitoneum can occur. Von Willebrand disease and afibrinogenemia are two important bleeding disorders in which both primary hemostasis and coagulation are involved. Bleeding during ovulation is one major clinical complication in women with these disease. We have studied three patients with this hemorrhagic complication. Our data show that oral contraceptives are an effective way to avoid hemoperitoneum.
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Authors | E Bottini, F I Pareti, D Mari, P M Mannucci, M L Muggiasca, M Conti |
Journal | Haematologica
(Haematologica)
1991 Sep-Oct
Vol. 76
Issue 5
Pg. 431-3
ISSN: 0390-6078 [Print] Italy |
PMID | 1806451
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Contraceptives, Oral, Hormonal
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Topics |
- Adult
- Afibrinogenemia
(complications)
- Blood Transfusion
- Combined Modality Therapy
- Contraceptives, Oral, Hormonal
(therapeutic use)
- Female
- Hemoperitoneum
(etiology, prevention & control, therapy)
- Humans
- Ovarian Follicle
- Ovulation
(drug effects)
- Rupture, Spontaneous
- von Willebrand Diseases
(complications)
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