Efficacy of intravitreal triamcinolone acetonide for eyes with postvitrectomy diabetic vitreous hemorrhage.

Abstract

PURPOSE:

To evaluate the efficacy of intravitreal triamcinolone acetonide (IVT) for the management of postvitrectomy diabetic vitreous hemorrhage.

METHODS:

The authors conducted a retrospective study of patients with postvitrectomy diabetic vitreous hemorrhage who were administered 4 mg (0.1 cc) of triamcinolone acetonide ophthalmic suspension. Ocular history, adverse events, BCVA, intraocular pressure, external eye examination, slit-lamp biomicroscopy, fundus examination, B-scan ultrasonography, and fundus photography were assessed on day 1, weeks 1, 2, and 4 and months 2 and 3.

RESULTS:

There were 19 eyes of 18 consecutive patients with mean follow-up after IVT injection of 28 weeks. Of the 19 eyes, 17 eyes (89%) experienced clearing of vitreous hemorrhage within 1 to 5 weeks (mean, 1.7 weeks) with visible triamcinolone precipitates along with blood clot in the inferior aspect of fundus. Of these 17 eyes, 12 eyes (63%) maintained vitreous hemorrhage-free condition at last follow-up with a mean visual acuity of 20/63 (range, 20/320 20/25), whereas 5 (29%) developed recurrent vitreous hemorrhage after clearing of vitreous hemorrhage. Vitreous hemorrhage was not cleared in 2 eyes, which required surgical procedures.

CONCLUSIONS:

IVT injection may be beneficial for clearing recurrent postvitrectomy Diabetic Vitreous Hemorrhage.

• Authors: Sun Young Lee, Hee Gyung Lee, Hye-won Chung, Young Hee Yoon, June-Gone Kim
• Journal: Korean journal of ophthalmology : KJO (Korean J Ophthalmol) Vol. 21 Issue 4 Pg. 208-12 (Dec 2007) ISSN: 1011-8942 [Print] Korea (South)
• PMID: 18063884 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Glucocorticoids
• Triamcinolone Acetonide

Topics

• Adult
• Aged
• Diabetic Retinopathy (complications, diagnosis)
• Female
• Follow-Up Studies
• Glucocorticoids (administration & dosage)
• Humans
• Injections
• Male
• Microscopy, Acoustic
• Middle Aged
• Postoperative Hemorrhage (diagnosis, drug therapy, etiology)
• Retrospective Studies
• Time Factors
• Treatment Outcome
• Triamcinolone Acetonide (administration & dosage)
• Visual Acuity
• Vitrectomy (adverse effects)
• Vitreous Body
• Vitreous Hemorrhage (diagnosis, drug therapy, etiology)