Inflammatory myopathy with anti-Golgi antibody and anti-SS-A/Ro antibody.

Abstract

We report a 74-year-old woman with anit-Golgi antibody and anti-SS-A/Ro antibody who contracted inflammatory myopahy presenting 'ALS-like' symptoms. We identified anti-Golgi antibody directly using confocal microscopy and successfully treated her with steroid. This report suggests that there is a new categorized subgroup of inflammatory myopathy with these specific antibodies and the pattern of autoantibody in these patients indicates the specific clinical course and treatment strategy.

• Authors: Hidenori Hattori, Eiichiro Nagata, Tadayuki Ishihara, Kiyo Jinnouchi, Yoko Ogawa, Toshihiro Nagai, Shigeaki Suzuki, Toshihiko Shimizu, Junichi Hamada, Norihiro Suzuki
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 46 Issue 23 Pg. 1927-30 ( 2007) ISSN: 1349-7235 [Electronic] Japan
• PMID: 18057767 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antibodies, Antinuclear
• Autoantigens
• SS-A antibodies

Topics

• Aged
• Antibodies, Antinuclear (analysis, immunology)
• Autoantigens (immunology)
• Female
• Golgi Apparatus (immunology)
• Humans
• Microscopy, Confocal
• Myositis (immunology)