Diffuse lamellar keratitis after corneal crosslinking in a patient with post-laser in situ keratomileusis corneal ectasia.

Abstract

A 27-year-old man presented with corneal ectasia in his left eye 4 years after myopic laser in situ keratomileusis (LASIK) and was treated with riboflavin-ultraviolet-A (crosslinking). During the first post-treatment days, diffuse lamellar keratitis (DLK) (stage III) developed. The microbiology culture was negative. After intensive treatment with topical corticosteroids, the DLK resolved during the following 2 weeks. Crosslinking for post-LASIK corneal ectasia may induce DLK. Early diagnosis and appropriate treatment with intensive topical corticosteroids is essential to successfully manage this post-crosslinking complication.

• Authors: George D Kymionis, Dimitrios I Bouzoukis, Vasilios F Diakonis, Dimitra M Portaliou, Aristofanis I Pallikaris, Sonia H Yoo
• Journal: Journal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 33 Issue 12 Pg. 2135-7 (Dec 2007) ISSN: 0886-3350 [Print] United States
• PMID: 18053917 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Photosensitizing Agents
• Dexamethasone
• Collagen
• Riboflavin

Topics

• Adult
• Collagen (metabolism)
• Corneal Diseases (drug therapy, etiology, metabolism)
• Dexamethasone (therapeutic use)
• Dilatation, Pathologic (drug therapy, etiology, metabolism)
• Glucocorticoids (therapeutic use)
• Humans
• Keratitis (drug therapy, etiology)
• Keratomileusis, Laser In Situ (adverse effects)
• Male
• Myopia (surgery)
• Photosensitizing Agents (adverse effects)
• Riboflavin (adverse effects)
• Ultraviolet Rays