[Efficiency of preemptive intravenous paracetamol analgesia in abdominal surgery].

Abstract

In a randomized, controlled study, 50 patients underwent elective surgery for abdominal cancer lesions under perioperative epidural analgesia. All the patients were randomized to receive paracetamol in a single intravenous dose of 1 g or placebo 30 minutes prior to the start of surgery. The use of 1 g of paracetamol as a single intravenous preemptive dose in abdominal surgery with perioperative epidural analgesia does not reduce the consumption of the analgesic and the intensity of pain in the postoperative period.

• Authors: D B Borisov, A V Levin, I V Vyl'iurov, A V Sokolov, E V Nedashkovskiĭ
• Journal: Anesteziologiia i reanimatologiia (Anesteziol Reanimatol) 2007 Sep-Oct Issue 5 Pg. 38-40 ISSN: 0201-7563 [Print] Russia (Federation)
• PMID: 18051491 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Analgesics, Non-Narcotic
• Acetaminophen

Topics

• Acetaminophen (administration & dosage, therapeutic use)
• Analgesia, Epidural (methods)
• Analgesics, Non-Narcotic (administration & dosage, therapeutic use)
• Colonic Neoplasms (surgery)
• Digestive System Surgical Procedures (methods)
• Female
• Humans
• Injections, Intravenous
• Male
• Middle Aged
• Pain Measurement
• Pain, Postoperative (prevention & control)
• Preoperative Care (methods)
• Stomach Neoplasms (surgery)
• Time Factors