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[Efficiency of preemptive intravenous paracetamol analgesia in abdominal surgery]

AbstractIn a randomized, controlled study, 50 patients underwent elective surgery for abdominal cancer lesions under perioperative epidural analgesia. All the patients were randomized to receive paracetamol in a single intravenous dose of 1 g or placebo 30 minutes prior to the start of surgery. The use of 1 g of paracetamol as a single intravenous preemptive dose in abdominal surgery with perioperative epidural analgesia does not reduce the consumption of the analgesic and the intensity of pain in the postoperative period.
AuthorsD B Borisov, A V Levin, I V Vyl'iurov, A V Sokolov, E V Nedashkovskiĭ
JournalAnesteziologiia i reanimatologiia (Anesteziol Reanimatol) 2007 Sep-Oct Issue 5 Pg. 38-40 ISSN: 0201-7563 Russia (Federation)
PMID18051491 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)
Chemical References
  • Analgesics, Non-Narcotic
  • Acetaminophen
Topics
  • Acetaminophen (administration & dosage, therapeutic use)
  • Analgesia, Epidural (methods)
  • Analgesics, Non-Narcotic (administration & dosage, therapeutic use)
  • Colonic Neoplasms (surgery)
  • Digestive System Surgical Procedures (methods)
  • Female
  • Humans
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Pain Measurement
  • Pain, Postoperative (prevention & control)
  • Preoperative Care (methods)
  • Stomach Neoplasms (surgery)
  • Time Factors