Abstract | PURPOSE: METHODS: Retrospective, observational case series of seven patients with Susac syndrome identified in ophthalmology and internal medicine departments. We reviewed medical, ophthalmologic, and angiographic records at study enrollment and during long-term treatment. Mean follow-up was 37 months. Best-corrected visual acuity, intraocular inflammation score, ophthalmoscopy data, automated perimetry score, and fluorescein and indocyanine green angiographic features were analyzed with the results of cerebral magnetic resonance imaging and spinal fluid analysis and ENT signs. RESULTS: CONCLUSION: Absence of intraocular inflammation and focal, labile nonperfused retinal arterioles with integrity of choroidal circulation are monomorphic ophthalmologic features that could immediately suggest the diagnosis of Susac syndrome. Early ophthalmologic examination aided by retinal fluorescein angiography could be useful for managing cases of unexplained neurologic symptoms in women.
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Authors | Nadege Martinet, Christine Fardeau, Raphael Adam, Bahram Bodaghi, Thomas Papo, Jean-Charles Piette, Phuc Lehoang |
Journal | Retina (Philadelphia, Pa.)
(Retina)
2007 Nov-Dec
Vol. 27
Issue 9
Pg. 1238-42
ISSN: 0275-004X [Print] United States |
PMID | 18046231
(Publication Type: Journal Article)
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Chemical References |
- Coloring Agents
- Glucocorticoids
- Immunosuppressive Agents
- Indocyanine Green
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Topics |
- Adult
- Cerebrovascular Disorders
(diagnosis, drug therapy)
- Cochlear Diseases
(diagnosis, drug therapy)
- Coloring Agents
- Female
- Fluorescein Angiography
- Follow-Up Studies
- Glucocorticoids
(therapeutic use)
- Humans
- Immunosuppressive Agents
(therapeutic use)
- Indocyanine Green
- Magnetic Resonance Imaging
- Middle Aged
- Ophthalmoscopy
- Prognosis
- Retinal Artery
(pathology)
- Retinal Artery Occlusion
(diagnosis, drug therapy)
- Retinal Vasculitis
(diagnosis, drug therapy)
- Retrospective Studies
- Syndrome
- Vision Disorders
(diagnosis, drug therapy)
- Visual Acuity
- Visual Fields
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