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Long-term outcomes of photorefractive keratectomy in eyes with previous epikeratophakia for keratoconus.

AbstractPURPOSE: To determine the long-term safety and effectiveness of photorefractive keratectomy (PRK) in the treatment of refractive errors after epikeratophakia (EP) for keratoconus. METHODS: Ten patients (14 eyes) who had refractive errors after EP for keratoconus received PRK surgery. Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), refractive error, corneal astigmatism, pachymetry, corneal topography, and complications were monitored. RESULTS: Mean follow-up after PRK was 63.4 +/- 19.8 months. Mean spherical equivalent was -5.5 +/- 3.9 D before PRK, -0.9 +/- 0.5 D at 1 month after PRK, and -1.5 +/- 1.0 D at 3 years. Mean astigmatism was 4.2 +/- 2.1 D before PRK, 1.2 +/- 0.5 D at 1 month after PRK, and 1.5 +/- 0.6 D at 3 years. Thirteen (93%) eyes had an UCVA <20/40, and 12 (86%) had a BSCVA of 20/40 or better before PRK. At 1 year, the UCVA was 20/40 or better in 8 (57%) eyes, and the BSCVA was 20/40 or better in all eyes. Mean central corneal thickness was 749 +/- 35 microm before PRK and 621 +/- 56 mum at 3 years. During the follow-up period, haze (grade no more than 1.0) was observed in 2 eyes. No immune rejection episode or recurrent keratoconus was found. CONCLUSIONS: PRK appears to be reliable and safe for the correction of residual ametropia after EP for keratoconus, and the visual acuity can remain stable after PRK for a long time.
AuthorsLixin Xie, Hua Gao, Weiyun Shi (Affiliation: State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China. lixinxie at public.qd.sd.cn)
JournalCornea (Cornea) Vol. 26 Issue 10 Pg. 1200-4 (Dec 2007) ISSN: 0277-3740 United States
PMID18043176 (Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Adolescent
  • Adult
  • Astigmatism (etiology, physiopathology, surgery)
  • Cornea (physiopathology)
  • Corneal Topography
  • Epikeratophakia (adverse effects)
  • Female
  • Follow-Up Studies
  • Graft Survival
  • Humans
  • Keratoconus (physiopathology, surgery)
  • Male
  • Myopia (etiology, physiopathology, surgery)
  • Photorefractive Keratectomy
  • Postoperative Complications
  • Retrospective Studies
  • Treatment Outcome
  • Visual Acuity (physiology)