| Abstract | PURPOSE: To determine the long-term safety and effectiveness of photorefractive keratectomy (PRK) in the treatment of refractive errors after epikeratophakia (EP) for keratoconus. METHODS: Ten patients (14 eyes) who had refractive errors after EP for keratoconus received PRK surgery. Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), refractive error, corneal astigmatism, pachymetry, corneal topography, and complications were monitored. RESULTS: Mean follow-up after PRK was 63.4 +/- 19.8 months. Mean spherical equivalent was -5.5 +/- 3.9 D before PRK, -0.9 +/- 0.5 D at 1 month after PRK, and -1.5 +/- 1.0 D at 3 years. Mean astigmatism was 4.2 +/- 2.1 D before PRK, 1.2 +/- 0.5 D at 1 month after PRK, and 1.5 +/- 0.6 D at 3 years. Thirteen (93%) eyes had an UCVA <20/40, and 12 (86%) had a BSCVA of 20/40 or better before PRK. At 1 year, the UCVA was 20/40 or better in 8 (57%) eyes, and the BSCVA was 20/40 or better in all eyes. Mean central corneal thickness was 749 +/- 35 microm before PRK and 621 +/- 56 mum at 3 years. During the follow-up period, haze (grade no more than 1.0) was observed in 2 eyes. No immune rejection episode or recurrent keratoconus was found. CONCLUSIONS: PRK appears to be reliable and safe for the correction of residual ametropia after EP for keratoconus, and the visual acuity can remain stable after PRK for a long time. |
| Authors | Lixin Xie, Hua Gao, Weiyun Shi
(Affiliation: State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China. lixinxie at public.qd.sd.cn)
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| Journal | Cornea
(Cornea)
Vol. 26
Issue 10
Pg. 1200-4
(Dec 2007)
ISSN: 0277-3740 United States |
| PMID | 18043176
(Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
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| Topics |
- Adolescent
- Adult
- Astigmatism
(etiology, physiopathology, surgery)
- Cornea
(physiopathology)
- Corneal Topography
- Epikeratophakia
(adverse effects)
- Female
- Follow-Up Studies
- Graft Survival
- Humans
- Keratoconus
(physiopathology, surgery)
- Male
- Myopia
(etiology, physiopathology, surgery)
- Photorefractive Keratectomy
- Postoperative Complications
- Retrospective Studies
- Treatment Outcome
- Visual Acuity
(physiology)
|