[The efficacy of foridon in treating stenocardia patients].

Abstract

A study is presented of the effect of a new native calcium antagonist foridon on the course of the disease central and peripheral hemodynamics, fatty metabolism, lipid peroxidation intensity, activity of ceruloplasmin and catalase, iron and chromium saturation of transferrin, content of cyclic nucleotides in thrombocytes, the state of cellular immunity and the number of circulating immune complex in 30 patients with advancing and stable exertion stenocardia (control--30 analogous patients treated by phynoptin and corinfar). It was established that foridon produced a positive effect on the intensity of the pain syndrome, hemodynamics, degree of lipid peroxidation, content of cyclic nucleotides and immune status of stenocardia patients.

• Authors: I H Kupnovyts'ka, S M Chuklin
• Journal: Vrachebnoe delo (Vrach Delo) Issue 10 Pg. 87-9 (Oct 1991) ISSN: 0049-6804 [Print] Ukraine
• Vernacular Title: Efektyvnist' forydonu pry likuvanni khvorykh na stenokardiiu.
• PMID: 1803758 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Calcium Channel Blockers
• Nitrates
• Vasodilator Agents
• Nifedipine
• ryodipine

Topics

• Adult
• Aged
• Angina Pectoris (blood, drug therapy, immunology, physiopathology)
• Calcium Channel Blockers (therapeutic use)
• Drug Evaluation
• Drug Therapy, Combination
• Humans
• Immunity, Cellular (drug effects)
• Middle Aged
• Nifedipine (analogs & derivatives, therapeutic use)
• Nitrates (therapeutic use)
• Vasodilator Agents (therapeutic use)