[Prokinetic agents as a cause of granulomatous interstitial nephritis].

Abstract

Granulomatous interstitial nephritides are uncommon entities in routine clinical practice. These entities are usually associated with infectious diseases such as tuberculosis, or immune diseases, such as sarcoidosis, systemic lupus erythematosus or cryoglobulinemia. However, these diseases are most frequently associated with drug intake, especially antibiotics, proton pump inhibitors and nonsteroidal anti inflammatory drugs. An association with prokinetic agents has not previously been reported. We report the case of a 64-year-old woman who developed acute renal failure with this histological pattern after taking the motility promoter cinitapride without her physician's knowledge.

• Authors: Ernesto J Fernández Tagarro, Raquel de Gracia Núñez, Rafael J Sánchez Villanueva, Carmen Riñón Aguilar, Rafael Selgas Gutiérrez
• Journal: Gastroenterologia y hepatologia (Gastroenterol Hepatol) Vol. 30 Issue 10 Pg. 583-4 (Dec 2007) ISSN: 0210-5705 [Print] Spain
• Vernacular Title: Procinéticos como causantes de nefritis intersticial granulomatosa.
• PMID: 18028853 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Benzamides
• cinitapride

Topics

• Benzamides (adverse effects)
• Female
• Humans
• Middle Aged
• Nephritis, Interstitial (chemically induced)