| Abstract | This article describes a case of severe opioid-induced pruritus following systemic morphine administration. Symptoms did not resolve after administration of antihistamines or rotation to fentanyl or hydromorphone, but oral oxycodone and small-dose intravenous naloxone did alleviate the patient's itching. The pathogenesis of opioid-induced pruritus and the rationale for opioid rotation are briefly discussed. Current and possible future therapeutic options are mentioned. |
| Authors | Dana Tarcatu, Cristina Tamasdan, Natalie Moryl, Eugenie Obbens
(Affiliation: Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.)
|
| Journal | Journal of opioid management
(J Opioid Manag)
2007 May-Jun
Vol. 3
Issue 3
Pg. 167-70
ISSN: 1551-7489 United States |
| PMID | 18027543
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Analgesics, Opioid
- Morphine
|
| Topics |
- Adolescent
- Analgesics, Opioid
(administration & dosage, adverse effects)
- Humans
- Male
- Morphine
(administration & dosage, adverse effects)
- Pain
(drug therapy)
- Pruritus
(chemically induced)
|
