Abstract |
The MeOH and CHCl3 extracts of the pericarps of Mallotus japonicus showed potential anti-tumor-promoter activity. Seven constituents of the CHCl3 extract and two derivatives from the most abundant constituent, mallotojaponin, markedly inhibited the incorporation of 3H-choline into phospholipids of C3H101/2 cells enhanced by 12-O-tetradecanoylphorbol-13-acetate (TPA), a potent tumor promoter.
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Authors | M Arisawa, A Fujita, N Morita, T Okuyama, H Nishino |
Journal | Journal of natural products
(J Nat Prod)
Vol. 54
Issue 5
Pg. 1409-12
( 1991)
ISSN: 0163-3864 [Print] United States |
PMID | 1800639
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anticarcinogenic Agents
- Phospholipids
- Phloroglucinol
- Choline
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Topics |
- Anticarcinogenic Agents
(chemistry, isolation & purification, pharmacology)
- Cell Line
- Choline
(metabolism)
- Phloroglucinol
(analogs & derivatives, isolation & purification, pharmacology)
- Phospholipids
(metabolism)
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