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[Adult living donor liver transplantation using right lobe for severe hepatitis in emergency: a report of 9 cases]

AbstractOBJECTIVE: To evaluate the outcome of emergency adult right lobe living donor liver transplantation for fulminant hepatitis. METHODS: Nine cases of adult right lobe living donor liver transplantation were performed from September 2002 to August 2005, the clinical and follow-up data was analyzed. RESULTS: According to Child Pugh Turcotte (CPT) classification, 9 patients were classified as grade C before transplant. The Model for End-Stage Liver Disease (MELD) scores of these patients were 26.7 +/- 8.8. The principal pre-transplant complications included hepatic encephalopathy (5 cases), electrolyte disturbance (3 cases), renal failure (2 cases), gastrointestinal bleeding (1 case). The operations in donors and recipients were all successful. The post-transplant complications induced pulmonary infection in 2 patients, acute renal failure in 3 and transplantation related encephalopathy in 1. There were no primary graft non-function and no blood vessel and bile tract complications occurred. One-year survival rate was 55.6%. No serious complication or death found in donors. CONCLUSIONS: Emergency adult to adult living donor liver transplantation is an effective treatment for fulminant hepatitis but the safety of the donors should be assessed strictly preoperation.
AuthorsFeng Zhang, Xue-Hao Wang, Xiang-Cheng Li, Lian-Bao Kong, Bei-Cheng Sun, Guo-Qiang Li, Xiao-Feng Qian, Feng Cheng, Sen Lu, Ling Lü (Affiliation: Center of Liver Transplantation, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210009, China.)
JournalZhonghua wai ke za zhi [Chinese journal of surgery] (Zhonghua Wai Ke Za Zhi) Vol. 45 Issue 15 Pg. 1019-22 (Aug 1 2007) ISSN: 0529-5815 China
PMID18005579 (Publication Type: English Abstract, Journal Article)