| Abstract | The efficacy of TIKLO was compared with acetylsalicylic acid in treatment of patients with intermittent claudication. Patients were divided into 2 groups (30 and 33 subjects). The first group received TIKLO (250 mg, BID), the second one - Thrombo ASS (100 mg, QD). Outcome measures included platelet aggregation, walking distance and the time of ankle-brachial index (ABI) recovery after treadmill test. TIKLO was shown to reduce platelet aggregation, increase pain-free walking distance and decrease the time of ABI recovery after treadmill test. TIKLO administration was accompanied with minimal adverse events. |
| Authors | I I Zatevakhin, V N Zolkin, E E Shiller |
| Journal | Angiologii͡a i sosudistai͡a khirurgii͡a = Angiology and vascular surgery
(Angiol Sosud Khir)
Vol. 13
Issue 2
Pg. 19-23
( 2007)
ISSN: 1027-6661 Russia (Federation) |
| PMID | 18004255
(Publication Type: Case Reports, English Abstract, Journal Article, Randomized Controlled Trial)
|
| Chemical References |
- Platelet Aggregation Inhibitors
- Ticlopidine
|
| Topics |
- Aged
- Atherosclerosis
(drug therapy, epidemiology, physiopathology)
- Exercise Test
- Female
- Humans
- Intermittent Claudication
(diagnosis, drug therapy, epidemiology)
- Lower Extremity
(blood supply, physiopathology)
- Male
- Movement Disorders
(epidemiology, etiology)
- Myocardial Ischemia
(drug therapy, epidemiology)
- Platelet Aggregation Inhibitors
(therapeutic use)
- Severity of Illness Index
- Ticlopidine
(therapeutic use)
- Treatment Outcome
|
