Determination of the lesion size in Laser-induced Interstitial Thermal Therapy (LITT) using a low-field MRI.

Abstract

This study aimed to compare MR thermal mapping during Laser-induced Interstitial Thermal Therapy (LITT) to thermal lesions observed macroscopically, in order to estimate the 3D size of the coagulative necrosis. Laser irradiation was performed ex-vivo with a 980 nm laser in pig liver in a open low-magnetic field (0.2T) scanner. The laser light was transmitted through a 1040/600 microm (outer/core diameter) bare-tip silica fiber. The laser energy was applied on a pulsed mode (10 s laser-on, 10 s laser-off) for 12 minutes, power: 6W, energy: 2160 J. MR thermal mapping used T1 method for its simplicity and its efficiency at low magnetic field.

• Authors: Romain Viard, Aline Emptaz, Bérengère Piron, Philippe Rochon, Benjamin Wassmer, Serge Mordon
• Journal: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference (Annu Int Conf IEEE Eng Med Biol Soc) Vol. 2007 Pg. 214-7 ( 2007) ISSN: 2375-7477 [Print] United States
• PMID: 18001927 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Humans
• Hyperthermia, Induced (instrumentation, methods)
• Laser Therapy (methods)
• Liver Neoplasms (pathology, secondary, therapy)
• Magnetic Resonance Imaging (instrumentation, methods)
• Models, Biological
• Predictive Value of Tests