Abstract | OBJECTIVE: METHODS: RESULTS: For mild or moderate benzene poisoning, the increase of WBC and RLT in CIK group was higher than that in the control group (P < 0.05). The CD(4)/CD(8) levels were significantly increased after CIK treatment. And for severe benzene poisoning, the effective rate of the CIK group was 91.7% and the mortality rate was 0%. CONCLUSION: CIK treatment is safe and effective for hematopoietic injury caused by benzene poisoning. The mechanism may be related with the immune modulation of CIK treatment on immunodeficiency of patients with benzene poisoning.
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Authors | Wei-wei Liu, Jia-yu Chen, Wei Yu, Zhi-qian Yang, Lv-bo Wu, Cheng Zhang, De-mao Yang |
Journal | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
(Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi)
Vol. 25
Issue 9
Pg. 546-9
(Sep 2007)
ISSN: 1001-9391 [Print] China |
PMID | 17997890
(Publication Type: Controlled Clinical Trial, English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Benzene
(poisoning)
- Cytokine-Induced Killer Cells
(immunology)
- Female
- Follow-Up Studies
- Humans
- Immunotherapy
- Male
- Middle Aged
- Treatment Outcome
- Young Adult
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