A preliminary report on ABO incompatible bone marrow transplant.

Abstract

Between September 1985 and June 1990, five patients with major and six patients with minor ABO blood group incompatibility between donor and recipient underwent allogeneic bone marrow transplantation (BMT) in the Singapore General Hospital. The period to engraftment, rate of recovery of peripheral blood leukocytes, granulocytes, and platelets and the incidence of graft versus host disease (GVHD) was similar to that observed following ABO blood group compatible marrow transplant. Erythroid development and reticulocytosis were, however, significantly delayed in patients receiving major ABO incompatible marrow transplant.

• Authors: P Tan, Y W Ong, S L Tien, T F Loh, S T Lim
• Journal: Annals of the Academy of Medicine, Singapore (Ann Acad Med Singap) Vol. 20 Issue 4 Pg. 421-8 (Jul 1991) ISSN: 0304-4602 [Print] Singapore
• PMID: 1799251 (Publication Type: Comparative Study, Journal Article)

Chemical References

• ABO Blood-Group System
• HLA Antigens

Topics

• ABO Blood-Group System (immunology)
• Adolescent
• Adult
• Bone Marrow Transplantation (immunology, methods)
• Dose-Response Relationship, Immunologic
• Female
• Graft Survival (immunology)
• Graft vs Host Disease (prevention & control)
• HLA Antigens (immunology)
• Histocompatibility (immunology)
• Humans
• Immunosuppression Therapy (methods)
• Male