Abstract | PURPOSE OF REVIEW: The most relevant advances in the field of paraneoplastic neurological syndromes are described, with special emphasis on particular clinical-immunological associations and practical issues for the diagnosis and treatment of these disorders. RECENT FINDINGS: SUMMARY: Neurologists must be aware of neurological syndromes that may have a paraneoplastic origin. Detection of onconeural antibodies is crucial to make the correct diagnosis. Immunotherapy should be used, although the impact of the treatment is unclear in cases with irreversible neuronal damage.
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Authors | Francesc Graus, Josep Dalmau |
Journal | Current opinion in neurology
(Curr Opin Neurol)
Vol. 20
Issue 6
Pg. 732-7
(Dec 2007)
ISSN: 1350-7540 [Print] England |
PMID | 17992098
(Publication Type: Journal Article, Review)
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Chemical References |
- Antigens, Surface
- Autoantibodies
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Topics |
- Antigens, Surface
(immunology)
- Autoantibodies
(immunology)
- Brain Diseases
(diagnosis, immunology, physiopathology)
- Diagnosis, Differential
- Early Diagnosis
- Humans
- Immunotherapy
(methods, trends)
- Neoplasms
(complications, immunology)
- Nervous System
(immunology, physiopathology)
- Paraneoplastic Syndromes, Nervous System
(diagnosis, immunology, physiopathology)
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