Abstract |
Fifteen children with gastro-esophageal reflux took part in a treatment trial with a regimen of magnesium hydroxide and aluminium hydroxide for 8 weeks period (700 mmol/1.73 mq/die). All children were evaluated clinically and underwent a 24-hour continuous esophageal pH-monitoring both at diagnosis and after 8 weeks of treatment. After therapy 12/15 children were cured and 3/15 improved. Moreover the total percentage of time during which pH was less than 4, the number of reflux episodes and the number of refluxes lasting than 5' recorded during 24-hour continuous esophageal pH-monitoring were significantly reduced after treatment. The Authors conclude that antacids in large quantities are effective in medical treatment of gastro-esophageal reflux.
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Authors | G Iacono, A Carroccio, G Montalto, F Cavataio, S Ippolito, I Kazmierska, V Balsamo |
Journal | Minerva pediatrica
(Minerva Pediatr)
Vol. 43
Issue 12
Pg. 797-800
(Dec 1991)
ISSN: 0026-4946 [Print] Italy |
Vernacular Title | Idrossido di magnesio e idrossido di alluminio nel trattamento del reflusso gastro-esofageo. |
PMID | 1798406
(Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article)
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Chemical References |
- Antacids
- Drug Combinations
- aluminum hydroxide, magnesium hydroxide, drug combination
- Aluminum Hydroxide
- Magnesium Hydroxide
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Topics |
- Aluminum Hydroxide
(therapeutic use)
- Antacids
(therapeutic use)
- Child
- Child, Preschool
- Drug Combinations
- Female
- Gastroesophageal Reflux
(diagnosis, drug therapy)
- Humans
- Hydrogen-Ion Concentration
- Infant
- Magnesium Hydroxide
(therapeutic use)
- Male
- Monitoring, Physiologic
- Time Factors
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