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[Hypereosinophilic asthma]

AbstractAlthough moderate airway infiltration by eosinophils is present in the eosinophilic inflammatory phenotype of asthma, hypereosinophilic asthma differs in its frankly elevated levels of eosinophils in the blood, induced sputum, and bronchoalveolar lavage. Some etiologic pitfalls may be tricky especially wheezing in eosinophilic pneumonia induced by drugs or parasitic infections. Idiopathic chronic eosinophilic pneumonia is associated with asthma in most cases. Churg-Strauss syndrome has asthma as a basic feature, but true systemic vasculitis with antineutrophil cytoplasmic autoantibodies is not always present. Systemic corticosteroids are the mainstay of treatment of most hypereosinophilic asthma patients.
AuthorsJean-François Cordier (Affiliation: Service de pneumologie, Centre de référence des maladies orphelines pulmonaires, Hôpital Louis Pradel, F-69677 Bron Cedex, France. jean-francois.cordier at chu-lyon.fr)
JournalPresse médicale (Paris, France : 1983) (Presse Med) Vol. 37 Issue 1 Pt 2 Pg. 167-72 (Jan 2008) ISSN: 0755-4982 France
Vernacular TitleAsthme hyperéosinophilique.
PMID17980546 (Publication Type: English Abstract, Journal Article, Review)
Topics
  • Asthma (complications)
  • Eosinophilia (complications)
  • Humans