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Side effects of pharmacotherapy on bone with long-acting gonadorelin agonist triptorelin for paraphilia.

AbstractINTRODUCTION:
There have been limited research studies concerning the use of libido inhibitors for the treatment of patients with a paraphilia. Observational studies suggest that agents that lower testosterone are an effective treatment for paraphilia.
AIM:
We report a case of hormonal treatment of paraphilia that was associated with side effects.
METHOD:
A 35-year-old man with a paraphilia was treated with long-acting gonadorelin.
RESULTS:
The desired result was reduced preoccupation with sexuality, but there were various side effects including a serious amount of bone loss.
CONCLUSION:
We believe that more attention should be given to the adverse effects of long-term treatment with triptorelin. In our view the drug regime needs to be revised.
AuthorsJohn Hoogeveen, Eveline Van der Veer
JournalThe journal of sexual medicine (J Sex Med) Vol. 5 Issue 3 Pg. 626-30 (Mar 2008) ISSN: 1743-6109 [Electronic] Netherlands
PMID17971105 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Triptorelin Pamoate
  • Gonadotropin-Releasing Hormone
Topics
  • Adult
  • Bone Density (drug effects)
  • Gonadotropin-Releasing Hormone (agonists)
  • Humans
  • Male
  • Osteoporosis (chemically induced)
  • Paraphilic Disorders (drug therapy)
  • Treatment Outcome
  • Triptorelin Pamoate (administration & dosage, adverse effects)

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