[Effect of Penqiangyan Granule on the immune function of patients with chronic pelvic inflammatory disease of blood-stasis and Shen-deficiency syndrome type].

Abstract

OBJECTIVE:

To explore the effect of Penqiangyan Granule (PG) on the immunity of patients with chronic pelvic inflammatory disease (CPID) of blood stasis and Shen-deficiency syndrome (BSSDS) type.

METHODS:

Sixty patients were randomly assigned to two groups: the treatment group treated with PG and the control group with Penyanjing Granule, 30 cases in each group. The treatment course was 4 weeks for both groups. The clinical efficacy, plasma levels of CD4 and CD8, and the serum levels of tumor necrosis factor-alpha (TNF-alpha) and interleukin-2 (IL-2) were measured before and after treatment.

RESULTS:

After treatment, the total effective rate in the treatment group and the control group was 96.7% and 63.3% respectively with significant difference between groups (P < 0.05); in the treatment group the plasma CD4, CD4/CD8 and serum IL-2 increased obviously, while the plasma CD8 and serum TNF-alpha decreased markedly (P < 0.05), all were significantly different with those in the control group (P < 0.05).

CONCLUSION:

PG can improve the immune function and alleviate inflammation in CPID patients of BSSDS type.

• Authors: Rui-Fen Liu, Xiao-Na Yang
• Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine (Zhongguo Zhong Xi Yi Jie He Za Zhi) Vol. 27 Issue 9 Pg. 841-3 (Sep 2007) ISSN: 1003-5370 [Print] China
• PMID: 17969902 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Drugs, Chinese Herbal
• Interleukin-2
• Tumor Necrosis Factor-alpha
• penqiangyan

Topics

• Adolescent
• Adult
• CD4-CD8 Ratio
• Chronic Disease
• Diagnosis, Differential
• Drugs, Chinese Herbal (therapeutic use)
• Female
• Humans
• Interleukin-2 (blood)
• Male
• Medicine, Chinese Traditional
• Middle Aged
• Pelvic Inflammatory Disease (diagnosis, drug therapy, immunology)
• Phytotherapy
• Syndrome
• Treatment Outcome
• Tumor Necrosis Factor-alpha (blood)
• Yang Deficiency (diagnosis, drug therapy, immunology)
• Young Adult