Intracranial hypertension associated with danazol withdrawal: a case report.

Abstract

Pseudotumor cerebri (PTC) is a seldom seen entity characterized by signs and symptoms associated with the intracranial hypertension (IH) without obvious causes. Some medical disorders and exogenous agents have been implicated in the development of PTC. Danazol is a popular gonadotropin inhibitor used for the treatment of endometriosis, breast disease and hereditary angioedema. While PTC has been occasionally reported in patients receiving danazol treatment, it is barely mentioned in those who discontinued danazol therapy abruptly. Here we report a case of IH developed soon after the withdrawal of danazol.

• Authors: Yi-Shan Wu, Shang-Der Chen, Tzu-Hui Li, Jia-Shou Liu, Min-Yu Lan, Yung-Yee Chang
• Journal: Acta neurologica Taiwanica (Acta Neurol Taiwan) Vol. 16 Issue 3 Pg. 173-6 (Sep 2007) ISSN: 1028-768X [Print] China (Republic : 1949- )
• PMID: 17966958 (Publication Type: Case Reports, Journal Article)

Chemical References

• Danazol

Topics

• Adult
• Danazol (adverse effects)
• Female
• Humans
• Pseudotumor Cerebri (diagnosis, etiology)