Abstract | PURPOSE: SETTING: Clínica Baviera, Instituto Oftalmológico Europeo, Madrid, Spain. METHODS: In this retrospective case series, the records of eyes with a history of ocular herpes that had LASIK from 2003 through 2005 were reviewed. The main outcome measure was postoperative recurrence of ocular herpes. RESULTS: Forty-nine eyes (48 patients) with a history of ocular herpes (HSV keratitis, 28 eyes; HSV eyelid lesions, 17 eyes; HZO, 4 eyes) were identified. All LASIK procedures were uneventful. Herpetic disease was inactive at the time of surgery in all eyes and for more than 1 year in 31 eyes. Perioperative antiviral systemic prophylaxis was used in 13 patients with a history of HSV keratitis. No eye developed reactivation of herpetic keratitis during the follow-up (range 1 to 28 months). CONCLUSIONS:
Laser in situ keratomileusis was safe in patients with a history of ocular herpes; no recurrences occurred during the follow-up period. However, candidates should be selected with caution and surgery performed only in eyes in which the herpes has been inactive for 1 year before surgery, without stromal disease, and with regular topography and pachymetry maps and normal corneal sensitivity. The most reasonable clinical strategy is perioperative systemic antiviral prophylaxis.
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Authors | Victoria de Rojas Silva, Rosa Rodríguez-Conde, Rosario Cobo-Soriano, Jaime Beltrán, Fernando Llovet, Julio Baviera |
Journal | Journal of cataract and refractive surgery
(J Cataract Refract Surg)
Vol. 33
Issue 11
Pg. 1855-9
(Nov 2007)
ISSN: 0886-3350 [Print] United States |
PMID | 17964388
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Antiviral Agents
(administration & dosage)
- Corneal Stroma
(surgery)
- Female
- Herpes Zoster Ophthalmicus
(complications)
- Herpesvirus 3, Human
(physiology)
- Humans
- Keratitis, Herpetic
(complications)
- Keratomileusis, Laser In Situ
(methods)
- Male
- Pilot Projects
- Recurrence
- Refractive Errors
(complications)
- Retrospective Studies
- Simplexvirus
(physiology)
- Virus Activation
(drug effects)
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