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Resolution of superior oblique myokymia with memantine.

AbstractWe describe a novel treatment of superior oblique myokymia. A 40-year-old woman was treated with gabapentin for this disorder with partial success and reported significant side effects including loss of libido and weight gain. After a drug holiday, memantine therapy was initiated resulting in a substantial improvement in her symptoms with far fewer side effects and stability on long-term maintenance therapy.
AuthorsSaurabh Jain, Shegufta J Farooq, Irene Gottlob (Affiliation: Leicester Royal Infirmary, Leicester, United Kingdom.)
JournalJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus (J AAPOS) Vol. 12 Issue 1 Pg. 87-8 (Feb 2008) ISSN: 1528-3933 United States
PMID17964207 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Dopamine Agents
  • Memantine
Topics
  • Administration, Oral
  • Adult
  • Diagnosis, Differential
  • Dopamine Agents (administration & dosage, therapeutic use)
  • Dose-Response Relationship, Drug
  • Eye Movements
  • Female
  • Follow-Up Studies
  • Humans
  • Magnetic Resonance Imaging
  • Memantine (administration & dosage, therapeutic use)
  • Myokymia (diagnosis, drug therapy, physiopathology)
  • Ocular Motility Disorders (diagnosis, drug therapy, physiopathology)
  • Oculomotor Muscles (physiopathology)