Abstract |
This study was to test the importance of patterns identification (PI) and the effectiveness of hwangryunhaedogtang ( huanglianjiedutang) (HT) treatment for patients with post stroke pathological laughter (PL). Fourteen subjects were enrolled. Eight subjects diagnosed with Yang Excess patterns (YEP) were assigned into group A and 6 subjects who had no YEP to group B. HT was administrated 3 times a day for 14 days to both groups. The duration of PL at one time, the frequency of PL in a day, and pathological laughter scale (PLS) were the primary outcome measures. Barthel index (BI) was the secondary outcome measure. The duration and the frequency of PL in group A were significantly decreased from 10.88 +/- 4.67 to 6.63 +/- 4.07 sec and from 6.38 +/- 2.72 to 3.00 +/- 1.77 times, respectively (p = 0.01) after 14 days administration of HT. PLS in group A was also significantly lowered from 9.13 +/- 1.73 to 4.75 +/- 0.71 points (p = 0.01). However, significant differences were not observed in BI in group A and in the primary and secondary outcome measures in group B. The duration and the frequency of PL and PLS were more markedly reduced in group A than in group B (p = 0.01, 0.02, and < 0.01, respectively). These results suggested that HT could be effective on subjects with post stroke PL diagnosed as YEP and PI, that prescription of herbal medications to such patients should be considered.
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Authors | Sang Pil Yun, Woo Sang Jung, Sung Uk Park, Sang Kwan Moon, Jung Mi Park, Chang Nam Ko, Ki Ho Cho, Young Suk Kim, Hyung Sup Bae |
Journal | The American journal of Chinese medicine
(Am J Chin Med)
Vol. 35
Issue 5
Pg. 725-33
( 2007)
ISSN: 0192-415X [Print] Singapore |
PMID | 17963313
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Aged
- Aged, 80 and over
- Female
- Humans
- Laughter
- Male
- Medicine, Chinese Traditional
- Middle Aged
- Plant Extracts
(therapeutic use)
- Stroke
(complications, physiopathology)
- Treatment Outcome
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