Abstract | WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: WHAT THIS STUDY ADDS: AIMS: METHODS: RESULTS: The 90% confidence interval of C(max), t(1/2) and CL/F of theophylline with 14-day danshen extract tablets vs. without comedication were (101.42, 121.36) (84.57, 106.72) and (88.82, 105.72), respectively. The time to peak plasma theophylline concentration was unchanged by danshen (P > 0.05). The pharmacokinetics parameter of theophylline was unaffected by danshen extract. CONCLUSIONS:
|
Authors | Furong Qiu, Guangji Wang, Yanan Zhao, Hua Sun, Guoguang Mao, Jiyi A, Jian Sun |
Journal | British journal of clinical pharmacology
(Br J Clin Pharmacol)
Vol. 65
Issue 2
Pg. 270-4
(Feb 2008)
ISSN: 1365-2125 [Electronic] England |
PMID | 17961194
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Drugs, Chinese Herbal
- Phenanthrolines
- dan-shen root extract
- Theophylline
|
Topics |
- Cross-Over Studies
- Drug Interactions
(physiology)
- Drugs, Chinese Herbal
(pharmacokinetics)
- Humans
- Phenanthrolines
(blood, pharmacokinetics)
- Salvia miltiorrhiza
- Theophylline
(blood, pharmacokinetics)
- Time Factors
|