| Abstract | Immunotherapy with Mycobacterium w was given, in addition to standard multidrug therapy (MDT) to a lepromatous leprosy (LL) patient with a bacteriological index (BI) of 6. After 15 months of treatment this patient attained bacteriological negativity and clinical inactivity. Histopathologically the patient upgraded to borderline-tuberculoid at 12 months, and at 15 months showed features of nonspecific infiltration in the dermis. The rapid immunological upgrading seen in the patient is highlighted in this paper. |
| Authors | S A Zaheer, N R Suresh, H K Kar, A K Sharma, A Mukherjee, R Mukherjee, G P Talwar
(Affiliation: National Institute of Immunology, New Delhi, India.)
|
| Journal | Leprosy review
(Lepr Rev)
Vol. 62
Issue 3
Pg. 297-302
(Sep 1991)
ISSN: 0305-7518 ENGLAND |
| PMID | 1795588
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Bacterial Vaccines
- Leprostatic Agents
- anti-leprosy vaccine
- Lepromin
|
| Topics |
- Bacterial Vaccines
(therapeutic use)
- Combined Modality Therapy
- Drug Therapy, Combination
- Humans
- Lepromin
(immunology)
- Leprostatic Agents
(administration & dosage)
- Leprosy, Lepromatous
(immunology, pathology, therapy)
- Male
- Middle Aged
- Mycobacterium leprae
(immunology)
|
