Abstract |
The duration of nephropathy, the onset of arterial hypertension (AH), a family history of AH, uric syndrome, intravenous urographic evidence, glomerular filtration rate (GFR) determined from endogenous creatinine, the cellular membranes studied in erythrocytes by ureal hemolysis, and blood levels of thiol and disulfide groups by back amperometric titration, red blood cell activity of glutathione reductase and glucoso-6-phosphate dehydrogenase were evaluated in 108 patients with essential hypertension (EH), mesangial proliferative glomerulonephritis who had elevated and normal blood pressures and 18 healthy subjects. All the patients underwent closed renal puncture biopsy. There were structural alterations in the red blood cell membranes as evidenced by examinations of glucose-6-phosphate dehydrogenase, thiol and disulfide groups in erythrocyte protein and low-weight molecular fractions in healthy subjects with a family history of AH, patients with EH, with mesangial proliferative glomerulonephritis. The abnormal uric syndrome was detected in patients with EH. Patients with AH displayed glomerular hyperfiltration and higher glomerular dimensions. Renal biopsy revealed adrenal interstitial sclerosis in patients with AH.
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Authors | B I Shulutko |
Journal | Kardiologiia
(Kardiologiia)
Vol. 31
Issue 8
Pg. 64-6
(Aug 1991)
ISSN: 0022-9040 [Print] Russia (Federation) |
Vernacular Title | Arterial'naia gipertenziia pri glomerulonefrite. |
PMID | 1795479
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Topics |
- Adult
- Biopsy
- Female
- Glomerular Filtration Rate
- Glomerulonephritis
(complications, diagnosis, pathology)
- Humans
- Hypertension
(etiology)
- Kidney
(pathology)
- Male
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