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Patients with presenting unusual manifestations with gestational trophoblastic neoplasm: case series and review of literatures.

Abstract
Early recognition of gestational trophoblastic neoplasms (GTN) will maximize the chances of cure with chemotherapy but some patients present with many different symptoms months or even years after the causative pregnancy making diagnosis difficult. Clinicians should be aware of the possibility of GTN in any reproductive age woman with bizarre central nervous system symptoms, gastrointestinal symptoms or radiographic evidence of metastatic tumor of unknown primary origin. We reported two cases of metastatic gestational trophoblastic neoplasms with bizarre pulmonary symptoms, one patient with small bowel metastasis, and two patients with brain metastasis presenting with unusual manifestations.
AuthorsTahereh Ashraf-Ganjooei, Fatemeh Ghaemmaghami
JournalArchives of gynecology and obstetrics (Arch Gynecol Obstet) Vol. 277 Issue 5 Pg. 465-70 (May 2008) ISSN: 0932-0067 [Print] Germany
PMID17940785 (Publication Type: Case Reports, Journal Article, Review)
Topics
  • Adult
  • Brain Neoplasms (complications, diagnosis, secondary)
  • Digestive System Neoplasms (complications, diagnosis, secondary)
  • Female
  • Gestational Trophoblastic Disease (complications, diagnosis, secondary)
  • Humans
  • Kidney Neoplasms (complications, diagnosis, secondary)
  • Pregnancy
  • Splenic Neoplasms (complications, diagnosis, secondary)

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