Proximal calciphylaxis treated with calcimimetic 'Cinacalcet'.

Abstract

Calciphylaxis is a rare condition affecting patients suffering from end-stage renal failure, characterised by cutaneous ischaemia and necrosis. The management of calciphylaxis is challenging owing to the lack of optimal medical therapy, although parathyroidectomy has shown some benefit. We present a case of severe proximal calciphylaxis treated with a small dose of the calcimimetic 'Cinacalcet'.

• Authors: Ismail A Mohammed, Vashisht Sekar, Abdullah J Bubtana, Sandip Mitra, Alastair J Hutchison
• Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (Nephrol Dial Transplant) Vol. 23 Issue 1 Pg. 387-9 (Jan 2008) ISSN: 0931-0509 [Print] England
• PMID: 17911087 (Publication Type: Case Reports, Journal Article)

Chemical References

• Naphthalenes
• Cinacalcet

Topics

• Abdomen
• Aged
• Calciphylaxis (drug therapy, etiology)
• Cinacalcet
• Fatal Outcome
• Female
• Hip
• Humans
• Kidney Failure, Chronic (complications)
• Naphthalenes (therapeutic use)