Abstract | OBJECTIVE: STUDY DESIGN AND SETTING: Retrospective clinical review at a tertiary care hospital. Seven patients with vocal process granulomas underwent percutaneous injection of botulinum toxin into both vocal folds, performed in an office setting. Total doses ranged from 10 to 25 U, divided between both vocal folds. RESULTS: All patients experienced resolution of their granulomas over two to seven weeks. No patient developed aspiration pneumonia. All patients experienced hoarseness secondary to the injections, but voice quality returned to baseline in all patients as the toxin was degraded. CONCLUSIONS: SIGNIFICANCE:
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Authors | E J Damrose, J F Damrose |
Journal | The Journal of laryngology and otology
(J Laryngol Otol)
Vol. 122
Issue 8
Pg. 824-8
(Aug 2008)
ISSN: 1748-5460 [Electronic] England |
PMID | 17908354
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Aged
- Botulinum Toxins, Type A
(administration & dosage)
- Combined Modality Therapy
- Drug Administration Schedule
- Follow-Up Studies
- Granuloma, Laryngeal
(drug therapy, pathology, surgery)
- Humans
- Injections
- Laryngoscopy
- Male
- Middle Aged
- Retrospective Studies
- Vocal Cords
(drug effects, pathology, surgery)
- Voice Quality
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