Multivessel coronary artery spasm refractory to intensive medical treatment.

Abstract

This case report describes multivessel coronary artery spasm refractory to oral nifedipine, intravenous isosorbide dinitrate, diltiazem and nicorandil, and intracoronary nitroglycerin. Intracoronary administration of nicorandil only transiently relieved coronary artery spasm. Prednisolone was effective in preventing coronary artery spasm.

• Authors: Tatsuhiko Asano, Yoshio Kobayashi, Masaki Ohno, Takashi Nakayama, Nakabumi Kuroda, Issei Komuro
• Journal: Angiology (Angiology) 2007 Oct-Nov Vol. 58 Issue 5 Pg. 636-9 ISSN: 0003-3197 [Print] United States
• PMID: 17906282 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Vasodilator Agents
• Nicorandil
• Prednisolone
• Diltiazem
• Nitroglycerin
• Nifedipine
• Isosorbide Dinitrate

Topics

• Administration, Oral
• Adult
• Angina Pectoris (drug therapy, etiology, pathology)
• Coronary Angiography
• Coronary Stenosis (complications, drug therapy, etiology, pathology)
• Coronary Vasospasm (complications, drug therapy, pathology)
• Diltiazem (therapeutic use)
• Electrocardiography
• Female
• Glucocorticoids (administration & dosage, therapeutic use)
• Humans
• Infusions, Intravenous
• Isosorbide Dinitrate (therapeutic use)
• Nicorandil (therapeutic use)
• Nifedipine (therapeutic use)
• Nitroglycerin (therapeutic use)
• Prednisolone (administration & dosage, therapeutic use)
• Treatment Failure
• Vasodilator Agents (administration & dosage, therapeutic use)