Multivessel coronary artery spasm refractory to intensive medical treatment.

This case report describes multivessel coronary artery spasm refractory to oral nifedipine, intravenous isosorbide dinitrate, diltiazem and nicorandil, and intracoronary nitroglycerin. Intracoronary administration of nicorandil only transiently relieved coronary artery spasm. Prednisolone was effective in preventing coronary artery spasm.
AuthorsTatsuhiko Asano, Yoshio Kobayashi, Masaki Ohno, Takashi Nakayama, Nakabumi Kuroda, Issei Komuro
JournalAngiology (Angiology) 2007 Oct-Nov Vol. 58 Issue 5 Pg. 636-9 ISSN: 0003-3197 [Print] United States
PMID17906282 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Glucocorticoids
  • Vasodilator Agents
  • Nicorandil
  • Prednisolone
  • Diltiazem
  • Nitroglycerin
  • Nifedipine
  • Isosorbide Dinitrate
  • Administration, Oral
  • Adult
  • Angina Pectoris (drug therapy, etiology, pathology)
  • Coronary Angiography
  • Coronary Stenosis (complications, drug therapy, etiology, pathology)
  • Coronary Vasospasm (complications, drug therapy, pathology)
  • Diltiazem (therapeutic use)
  • Electrocardiography
  • Female
  • Glucocorticoids (administration & dosage, therapeutic use)
  • Humans
  • Infusions, Intravenous
  • Isosorbide Dinitrate (therapeutic use)
  • Nicorandil (therapeutic use)
  • Nifedipine (therapeutic use)
  • Nitroglycerin (therapeutic use)
  • Prednisolone (administration & dosage, therapeutic use)
  • Treatment Failure
  • Vasodilator Agents (administration & dosage, therapeutic use)

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