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Degradation of the neolignan, burchellin in the hemolymph of the bloodsucking insect Rhodnius prolixus.

Abstract
The neolignan, burchellin, a natural compound that reduces urine excretion in larvae of the bloodsucking bug, Rhodnius prolixus, a vector of Chagas' disease, is rapidly degraded in the hemolymph of the insect. The main product that accumulates in this tissue has been shown to be piperonyl alcohol. Other catabolites have been identified by GC-MS analysis.
AuthorsMarise M O Cabral, Eloi S Garcia, Otto R Gottlieb, Alphonse Kelecom
JournalFitoterapia (Fitoterapia) Vol. 79 Issue 1 Pg. 59-63 (Jan 2008) ISSN: 1873-6971 [Electronic] Netherlands
PMID17904765 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Benzofurans
  • Benzyl Alcohols
  • Pesticides
  • Plant Extracts
  • burchellin
  • piperonyl alcohol
Topics
  • Animals
  • Benzofurans (blood, metabolism)
  • Benzyl Alcohols (metabolism)
  • Chagas Disease (prevention & control)
  • Hemolymph (metabolism)
  • Lauraceae
  • Pesticides (pharmacology)
  • Plant Extracts (metabolism)
  • Rhodnius (metabolism)
  • Structure-Activity Relationship

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