Abstract |
To examine the putative protective effect of disinfectant use on HIV seroconversion among intravenous drug users, we conducted a nested case-control study comparing 22 black heterosexual HIV seroconverters with 95 persistent seronegatives matched on gender, use of cocaine, date of study entry, and duration of follow-up. For intravenous drug users who reported using disinfectant all the time, the odds of seroconversion was 0.77 (95% CI: 0.25-2.38) compared with those who reported no use of disinfectants; for those who used disinfectants some of the time, the corresponding odds ratio was 0.91 (95% CI: 0.26-3.31). The odds ratio for use of disinfectant all the time was 0.63 (95% CI: 0.10-3.91) for those injecting at galleries and 1.08 (95% CI: 0.35-3.11) for those not injecting at galleries. These data suggest a limited protective effect of disinfectant use in the field which may be more beneficial to those injecting in shooting galleries.
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Authors | D Vlahov, A Muñoz, D D Celentano, S Cohn, J C Anthony, H Chilcoat, K E Nelson |
Journal | Epidemiology (Cambridge, Mass.)
(Epidemiology)
Vol. 2
Issue 6
Pg. 444-6
(Nov 1991)
ISSN: 1044-3983 [Print] United States |
PMID | 1790197
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Topics |
- Adult
- Baltimore
- Case-Control Studies
- Disinfection
- HIV Seropositivity
(epidemiology)
- Humans
- Logistic Models
- Needle Sharing
- Needles
- Odds Ratio
- Risk Factors
- Substance Abuse, Intravenous
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