Resolution of an oral ulcer secondary to acetaminophen/hydrocodone withdrawal.

Abstract

Acetaminophen/hydrocodone is a common non-opioid/opioid analgesic indicated for the treatment of moderate to severe pain. The following report depicts a unique case involving a 57-year-old woman with a persistent, painful oral ulcer that was unresponsive to standard treatments. The ulcer was resolved when the patient discontinued acetaminophen/hydrocodone use. The cause of the ulcer is unclear but it was speculated to result from a systemic hypersensitivity reaction to acetaminophen/hydrocodone.

• Authors: Ramesh Balasubramaniam, Po-Ching Lin, Dean K White, Juan F Yepes
• Journal: General dentistry (Gen Dent) 2007 Sep-Oct Vol. 55 Issue 5 Pg. 441-4 ISSN: 0363-6771 [Print] United States
• PMID: 17899723 (Publication Type: Case Reports, Journal Article)

Chemical References

• Analgesics, Opioid
• Drug Combinations
• acetaminophen, hydrocodone drug combination
• Acetaminophen
• Hydrocodone

Topics

• Acetaminophen (adverse effects)
• Analgesics, Opioid (adverse effects)
• Drug Combinations
• Drug Hypersensitivity (etiology)
• Female
• Humans
• Hydrocodone (adverse effects)
• Low Back Pain (drug therapy)
• Middle Aged
• Oral Ulcer (chemically induced)