Abstract | BACKGROUND: METHODS: RESULTS: DISCUSSION: This preliminary clinical experience suggests that the addition of caspofungin to trimethoprim-sulfamethoxazole, which is active against trophic forms, may provide a synergistic activity against P. jiroveci by fully inhibiting the organism life cycle.
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Authors | Riccardo Utili, Emanuele Durante-Mangoni, Cristina Basilico, Annunziata Mattei, Enrico Ragone, Paolo Grossi |
Journal | Transplantation
(Transplantation)
Vol. 84
Issue 6
Pg. 685-8
(Sep 27 2007)
ISSN: 0041-1337 [Print] United States |
PMID | 17893600
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Infective Agents
- Echinocandins
- Lipopeptides
- Peptides, Cyclic
- Trimethoprim, Sulfamethoxazole Drug Combination
- Caspofungin
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Topics |
- Adult
- Anti-Infective Agents
(therapeutic use)
- Caspofungin
- Drug Therapy, Combination
- Echinocandins
- Female
- Humans
- Immunosuppression Therapy
(adverse effects)
- Lipopeptides
- Male
- Middle Aged
- Organ Transplantation
- Peptides, Cyclic
(therapeutic use)
- Pneumonia, Pneumocystis
(drug therapy, immunology)
- Treatment Outcome
- Trimethoprim, Sulfamethoxazole Drug Combination
(therapeutic use)
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