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Catheter-based modification of heart valve diseases: from experimental to clinical application.

Abstract
Efforts to modify cardiac valve defects using catheter-based techniques are increasing at the present time. We present observations on cardiac valve morphology and disease and review the progress being made to address valve defects with these innovative methods. Some new procedures developed through animal experimentation have already been put to use in clinical practice, but the newness of these techniques and the small number of cases in which they have been applied to date precludes an evaluation of their long-term durability. Although at the present time cardiac surgery remains the standard for treating most cases of valve disease, in certain situations a catheter-based treatment might provide a reasonable alternative, even if only temporary, especially for individuals with serious disease who are not suitable candidates for surgery.
AuthorsJan Sochman, Jan H Peregrin
JournalASAIO journal (American Society for Artificial Internal Organs : 1992) (ASAIO J) 2007 Sep-Oct Vol. 53 Issue 5 Pg. 609-16 ISSN: 1538-943X [Electronic] United States
PMID17885335 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
Topics
  • Animals
  • Aortic Valve
  • Catheter Ablation (methods)
  • Heart Valve Diseases (surgery, therapy)
  • Heart Valve Prosthesis
  • Heart Valve Prosthesis Implantation (methods)
  • Humans
  • Mitral Valve
  • Models, Cardiovascular
  • Prosthesis Design
  • Pulmonary Artery
  • Pulmonary Valve
  • Treatment Outcome
  • Tricuspid Valve

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