Patient satisfaction with eletriptan in the acute treatment of migraine in primary care.

Abstract

OBJECTIVE:

The efficacy of triptans for acute migraine has been well established in clinical trials but not in primary care, where they are most commonly prescribed. The aim of this open-label study was to evaluate the effectiveness of eletriptan 40 mg in primary care, using a patient-weighted satisfaction scale.

METHODS:

Eligible patients met International Headache Society criteria for migraine, with 1-6 attacks per month. Patients completed questionnaires at screening and following a single eletriptan-treated attack. Treatment satisfaction was evaluated using a six-item Medication Satisfaction Questionnaire (MSQ). MSQ item scores were weighted, based on the important score ratings, to yield individualised satisfaction scores. The primary end-point was the difference in weighted satisfaction scores between the patient's previous treatment and eletriptan 40 mg. Secondary end-points assessed quality of life (QOL), functioning and efficacy of treatment.

RESULTS:

Of 590 patients screened, 437 completed the study. Degree (95.2%), time (88.8%) and duration (83.8%) of headache pain relief were rated as most important by patients. The mean (+/-SD) total satisfaction score on the MSQ was higher for eletriptan than previous therapy (2.2 +/- 3.0 vs. 0.6 +/- 2.4; p < 0.001). The high level of satisfaction with eletriptan vs. previous treatment reflects the improvements in QOL and functioning observed, and the high headache and pain-free response rates.

CONCLUSIONS:

Patient-weighted satisfaction with eletriptan 40 mg was higher than with previous treatment for all items. The use of patient-weighted importance ratings of satisfaction is a promising approach for establishing effectiveness of treatment in primary care.

• Authors: R B Nett, P J Tiseo, M Almas, C R Sikes
• Journal: International journal of clinical practice (Int J Clin Pract) Vol. 61 Issue 10 Pg. 1677-85 (Oct 2007) ISSN: 1368-5031 [Print] India
• PMID: 17877653 (Publication Type: Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)

Chemical References

• Pyrrolidines
• Serotonin Receptor Agonists
• Tryptamines
• eletriptan

Topics

• Acute Disease
• Adolescent
• Adult
• Aged
• Family Practice
• Female
• Humans
• Male
• Middle Aged
• Migraine Disorders (drug therapy)
• Pain Measurement
• Patient Satisfaction
• Pyrrolidines (adverse effects, therapeutic use)
• Quality of Life
• Serotonin Receptor Agonists (adverse effects, therapeutic use)
• Surveys and Questionnaires
• Treatment Outcome
• Tryptamines (adverse effects, therapeutic use)