| Abstract | A 70-year-old man with abdominal pain and anemia was diagnosed with duodenal cancer upon upper gastrointestinal endoscopy and biopsy. Pancreatoduodenectomy was performed. Pathological findings were duodenal cancer, T 4 SI (Panc) N0P0V0A0H0. Three months after operation, abdominal CT showed multiple liver metastasis. He then underwent combined chemotherapy consisting of two weeks administration of S-1 (80 mg/body) followed by one week rest and injections of docetaxel (40 mg/body) every three weeks as one course. Metastatic tumors were gradually reduced and successfully controlled,and there was no other recurrence until he died about three years later of another illness. Combined S-1 and docetaxel chemotherapy is known to be effective for esophageal cancer, gastric cancer and other digestive cancer, as well as for duodenal cancer. |
| Authors | Michihiro Ishida, Takefumi Niguma, Toshikazu Kimura, Tetushige Mimura, Nobumasa Tsutsui
(Affiliation: Department of Surgery, Okayama Saiseikai General Hospital.)
|
| Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 34
Issue 9
Pg. 1477-9
(Sep 2007)
ISSN: 0385-0684 Japan |
| PMID | 17876150
(Publication Type: Case Reports, English Abstract, Journal Article)
|
| Chemical References |
- Antineoplastic Agents
- Drug Combinations
- Taxoids
- docetaxel
- S 1 (combination)
- Tegafur
- Oxonic Acid
|
| Topics |
- Aged
- Antineoplastic Agents
(administration & dosage)
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Drug Combinations
- Duodenal Neoplasms
(drug therapy, pathology, surgery)
- Humans
- Liver Neoplasms
(drug therapy, secondary)
- Male
- Oxonic Acid
(administration & dosage)
- Taxoids
(administration & dosage)
- Tegafur
(administration & dosage)
|
