| Abstract | The authors confirmed the presence of endocrine cells for the first time in a normal breast as well as in a non-cancerous lesion of the breast. One hundred and eighty-eight blocks of normal breast tissues in 44 cases and 74 blocks of non-cancerous lesions in 35 cases were examined. Argyrophil cells were found in one block from a normal breast and in one block from a phyllodes tumor. Argyrophil cells in the normal breast showed positive reaction to anti-endocrine granule constituent (EGC) antibody with immunohistochemical method. Argyrophil cells found in the phyllodes tumor gave positive reaction to both anti-EGC and anti-serotonin antibodies. The present study is thought to be the first report in the literature of serotonin-positive cells in a non-cancerous breast lesion, a phyllodes tumor. |
| Authors | T Satake, M Matsuyama
(Affiliation: Department of Clinical Pathology, Nagoya Ekisaikai Hospital, Japan.)
|
| Journal | Acta pathologica japonica
(Acta Pathol Jpn)
Vol. 41
Issue 12
Pg. 874-8
(Dec 1991)
ISSN: 0001-6632 JAPAN |
| PMID | 1785346
(Publication Type: Journal Article)
|
| Chemical References |
|
| Topics |
- Adult
- Aged
- Aged, 80 and over
- Breast
(chemistry, cytology, pathology, ultrastructure)
- Breast Diseases
(metabolism, pathology)
- Breast Neoplasms
(chemistry, pathology)
- Cytoplasmic Granules
(chemistry)
- Female
- Fibrocystic Breast Disease
(metabolism, pathology)
- Humans
- Microscopy, Electron
- Middle Aged
- Serotonin
(analysis)
- Silver Staining
|
