Abstract | OBJECTIVE: MATERIAL AND METHODS: RESULTS: Of all parameters only CBG showed a significant difference (p = 0.0318) in its peak levels measured in the first 48 h in patients with sterile (26.5 microg/ml, range 21.3-34.7) and infected (16.0 microg/ml, range 15.2-25.0) necrosis at a cut-off level of 16.8 microg/ml. That difference was further preserved for the first 6 days after onset of pain. CONCLUSIONS: In our group of patients, a decreased CBG level below 16.8 g/ml within the initial 48 h of acute pancreatitis was an early predictor of later infected pancreatic necrosis, with a positive predictive value of 100% and a negative predictive value of 87.5%.
|
Authors | Christophe A Muller, Orlin Belyaev, Michael Vogeser, Dirk Weyhe, Beat Gloor, Oliver Strobel, Jens Werner, Anders Borgstrom, Markus W Buchler, Waldemar Uhl |
Journal | Scandinavian journal of gastroenterology
(Scand J Gastroenterol)
Vol. 42
Issue 11
Pg. 1354-61
(Nov 2007)
ISSN: 0036-5521 [Print] England |
PMID | 17852861
(Publication Type: Journal Article)
|
Chemical References |
- Adrenocorticotropic Hormone
- C-Reactive Protein
- Transcortin
- Hydrocortisone
|
Topics |
- Adolescent
- Adrenocorticotropic Hormone
(blood)
- Adult
- Aged
- Aged, 80 and over
- Bacterial Infections
(diagnosis)
- C-Reactive Protein
(analysis)
- Diagnosis, Differential
- Female
- Humans
- Hydrocortisone
(blood)
- Male
- Middle Aged
- Pancreatitis, Acute Necrotizing
(complications)
- Predictive Value of Tests
- Time Factors
- Transcortin
(analysis)
|